Mohi Ahmadinia
In a unique collaboration between the Delft University of Technology and Getinge Applikon two types of processes utilized for Evolutionary Engineering of Microorganisms, the Repeated Batch and Chemostat / Accelerostat processes, were optimized to minimize human involvement. The Lucullus® software package from Securecell AG was the key to automating these processes.
The Technical University of Delft (TU Delft) is a front-runner in the field of Evolutionary Engineering of Microorganisms. Directed evolution of microorganisms is a powerful tool for obtaining new mutant strains with new or improved characteristics, but in the past has been labor-intensive; the evolution of microorganisms takes place in laboratory-scale fermenters and such a process can last for months, requiring frequent care from the operators.
In this webinar, the following topics have been covered:
- Introduction to microbial evolution
- The power of evolutionary engineering
- Bioreactors: a brief overview
- Cultivation strategies in microbial evolution
- Introduction Lucullus®
- Protocol for automated evolution
- Q&A
Duration: 60 min
Speakers and contributors
Mohi Ahmadinia
