Insights

ENHANCED AAV2 PRODUCTION PROCESS CONTROL AND INSIGHT THROUGH INTEGRATION OF NUMERA® AUTOMATED SAMPLING AT CATAPULT

Written by Mohi Ahmadinia | Aug 22, 2024 1:00:00 AM

Image reference: Attached poster - published at Catapult (Cell and gene therapy)

This work was conducted at the newly established Cell and Gene Therapy Catapult PAT Laboratory, an advanced bioprocessing facility dedicated to fully automated sampling and real-time sample analysis. The laboratory is equipped with cutting-edge in-line and atline monitoring tools, complemented by multi-omics capabilities, enabling collaborators to identify and assess critical process parameters in real-time. Additionally, state-of-the-art automation and digitalization within the facility support swift and precise process control.

The Numera® autosampling system was employed to monitor an AAV2 production process, demonstrating comparable measurements for cell counting, metabolite profiling, and AAV2 quantification between manually and automatically collected samples. The system has since been integrated with the Lucullus® data management and capture platform, enabling centralized monitoring and control of AAV2 production experiments.


Image reference: Attached poster - published at Catapult (Cell and gene therapy)

 

Download a published poster from Catapult (Cell and gene therapy) in PDF

 

Reference:
Attached poster - published at Catapult (Cell and gene therapy)