Automated sampling in bioprocesses
High-frequent sampling of small volumes and precise analytics around the clock.
"Whether on- or off-line, Numera delivers accurate HPLC data fast and with little effort."
Dr. Ueli von Ah, Biotechnolgy Research Group Leader, Agroscope
"Numera improved the automation of our Continuous Countercurrent Tangential Chromatography (CCTC) System."
Oleg Shinkazh, CEO and Founder, ChromaTan Corp.
"High-density, time-resolved data reduce the number of experiments!"
Univ.-Prof. Dipl.-Ing. Dr. techn. Christoph Herwig, Professor for Biotchemical Engineering, TU Wien
Sampling and sample preparation in bioprocess development are often done manually. Therefore, deviations can occur, results are timely delayed, recorded manually and missing during weekends and nights. Numera is a modular system which provides an integrated and customized PAT solution. It enables on-line analytics for reliable results in real-time around the clock. Combined with Lucullus, the entire workflow of sampling, monitoring and feed-back control is covered by an all-in-one solution.
Gain efficiency
Biomass-containing samples are drawn from up to 16 bioreactors in high frequency, maintaining sterility, preventing cross-contamination and sample loss. Samples can be transferred to up to 4 coupled analyzers and one HPLC, optional with previous dilution, reagent addition and/or filtration.
Let’s talk about your specific solution
Key Functionalities
The unique automated sampling and sample processing system for on-line analytics in up- and down- stream bioprocesses.
Examples of Applications
Process transparency
Monitoring substrates, metabolites and products.
Closed-loop control
Feed-back control loop with Lucullus and Numera.
Monitoring CPP
High frequent and precise detection of limitations
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