Automated sampling in bioprocessing

High-frequency sampling of small volumes and precise analytics around the clock.

Lab Sampling and sample preparation in bioprocess development are often done manually. Therefore, deviations can occur, results are timely delayed, recorded manually and missing during weekends and nights. Numera® is a modular system which provides an integrated and customized process analytical technology (PAT) improvement. It enables on-line analytics for reliable results in real-time 24/7. Combined with Lucullus, the entire workflow of sampling design, systematic sampling automation, bioprocess monitoring, and feedback control is covered by an all-in-one solution.

Gain efficiency

Thanks to the sampling control system, the biomass-containing samples are drawn from up to 16 bioreactors in high frequency, maintaining sterility, preventing cross-contamination, fouling, and sample loss. Samples can be transferred to up to 4 coupled analyzers and one HPLC, optional with previous dilution, reagent addition, and/or filtration.


Accurate sample preparation leads to reliable data


Individually design sample processing and analysis


Gain knowledge in real-time for faster development

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Key Functionalities

The unique automated sampling and sample processing system for on-line analytics in up- and down- stream bioprocesses.

Automated sampling reliable 24/7

Monitoring substrates, metabolites and products.

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Closed-loop control

Feed-back control loop with Lucullus and Numera.

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See Application Notes